The ability to thrive in the face of organizational change is, in fact, a common challenge for leaders in organisations. The way changes recipients respond is undoubtedly one of the most important factors in determining how well any organizational change succeeds. An organisation must constantly change to keep up with industry changes if it wants to remain competitive. If the current leadership is not performing well, changing leadership is required. However, there aren't many studies that back up this assertion. This has necessitated a study on the applicability of change management and leadership in organisations that have merged or been acquired. Examining the value of change management and leadership in mergers and acquisitions with an emphasis on Ghana's banking industry is the aim of this study. Consolidated Bank Ghana data was extracted and analysed using a descriptive survey design. Profitability as a metric for two (2) years of organizational performance was extracted from the bank's records. The quantitative method was the research strategy used for this investigation. According to the study's findings, organizational performance in the banking industry with regard to mergers and acquisitions is influenced by both change management and leadership in a number of ways. Practically speaking, this study suggests that new banks focus mostly on change management and leadership. To align with the emerging external and internal pressures, these banks' leadership must embrace a transformational approach that facilitates change